The Longevity Index

A comprehensive registry of 52 compounds analyzed for their impact on cellular senescence, telomere biology, and biological age reduction.

Compound Relevance Primary Anti-Aging Benefit Targeted Hallmarks Profile
Cagrilintide
Long-Acting Amylin Analog
Core Longevity
Appetite control and weight management, especially synergistic with GLP-1 agonists.
Systemic
Epithalon
Epitalon
Core Longevity
Telomere lengthening, cellular longevity, and improved sleep quality.
Telomere AttritionEpigenetic AlterationsLoss of Proteostasis
GHK-Cu
Copper Peptide
Core Longevity
Skin regeneration, collagen synthesis, and systemic anti-aging gene activation.
Genomic InstabilityEpigenetic AlterationsCellular Senescence
GLP-1 (Semaglutide)
Semaglutide
Core Longevity
Significant weight loss via appetite suppression and metabolic improvement.
Deregulated Nutrient SensingChronic InflammationCellular Senescence
MOTS-C
Mitochondrial ORF of the 12S rRNA Type-C
Core Longevity
Metabolic regulation, insulin sensitivity improvement, and exercise mimetic effects.
Mitochondrial DysfunctionDeregulated Nutrient SensingStem Cell Exhaustion
NAD+
Nicotinamide Adenine Dinucleotide
Core Longevity
Cellular energy restoration, DNA repair activation, and anti-aging pathway stimulation.
Deregulated Nutrient SensingMitochondrial DysfunctionGenomic Instability
Pinealon
EDR Peptide
Core Longevity
Neuroprotection, sleep regulation, and pineal gland support.
Epigenetic AlterationsAltered Intercellular Communication
Thymalin
Thymus Gland Peptide Complex
Core Longevity
Immune system restoration and longevity support via thymus function normalization.
Altered Intercellular CommunicationEpigenetic Alterations
Thymosin Alpha-1
Thymalfasin
Core Longevity
Immune system modulation, T-cell function enhancement, and antiviral support.
Altered Intercellular CommunicationStem Cell Exhaustion
ARA-290
Cibinetide
Support
Tissue protection, neuropathy relief, and anti-inflammatory action.
Systemic
BPC-157
Body Protection Compound
Support
Accelerated tendon, ligament, and gut tissue repair.
Cellular SenescenceAltered Intercellular Communication
CJC-1295 (No DAC)
Mod GRF 1-29
Support
Pulsatile GH release that mimics natural GH secretion patterns.
Systemic
CJC-1295 with DAC
CJC-1295 DAC
Support
Sustained GH elevation with less frequent dosing.
Systemic
Glutathione
GSH
Support
Master antioxidant protection, skin brightening, and detoxification support.
Mitochondrial DysfunctionGenomic Instability
IGF-1 LR3
Long R3 IGF-1
Support
Enhanced anabolic effects and muscle growth with extended half-life.
Stem Cell ExhaustionDeregulated Nutrient Sensing
Ipamorelin
Ipamorelin Acetate
Support
Selective GH release with a favorable safety profile and minimal side effects.
Deregulated Nutrient SensingMitochondrial Dysfunction
KPV
Lys-Pro-Val
Support
Potent anti-inflammatory action, particularly for gut and skin inflammation.
Systemic
LL-37
Cathelicidin
Support
Antimicrobial action, wound healing, and innate immune activation.
Systemic
PNC-27
p53 N-terminal Peptide
Support
Selective cancer cell targeting without harm to normal cells.
Systemic
Sermorelin
GHRH 1-29
Support
Natural GH stimulation from the pituitary with a well-established safety record.
Deregulated Nutrient SensingMitochondrial Dysfunction
TB-500 (Thymosin Beta-4)
Thymosin Beta-4
Support
Systemic tissue regeneration, flexibility support, and wound healing.
Systemic
Tesamorelin
TH9507
Support
Visceral fat reduction and GH stimulation.
Systemic
AOD-9604
Anti-Obesity Drug 9604
Adjacent
Targeted fat metabolism and body composition improvement without GH-related side effects.
Systemic
BPC-157 + TB-500 + KPV Blend
Triple Recovery Blend
Adjacent
Comprehensive tissue repair with added anti-inflammatory and gut-healing support.
Systemic
BPC-157 + TB-500 Blend
BPC-157 TB-500 Stack
Adjacent
Comprehensive tissue repair and recovery via synergistic dual mechanism.
Systemic
BPC-157 Pro Delayed Release
Oral BPC-157
Adjacent
Gut-targeted tissue repair and anti-inflammatory action via convenient oral delivery.
Systemic
CJC-1295 + Ipamorelin Blend
GH Stack
Adjacent
Maximized pulsatile GH release with minimal side effects via dual receptor stimulation.
Systemic
DSIP
Delta Sleep-Inducing Peptide
Adjacent
Deep sleep promotion and sleep quality improvement.
Systemic
DSIP Nasal Spray
Delta Sleep Nasal Spray
Adjacent
Convenient deep sleep promotion via nasal delivery without injection.
Systemic
GHRP-2
Growth Hormone Releasing Peptide-2
Adjacent
Strong GH release with appetite stimulation.
Systemic
GHRP-6
Growth Hormone Releasing Peptide-6
Adjacent
GH release with pronounced appetite stimulation — useful for bulking phases.
Systemic
GLP-2
Glucagon-Like Peptide-2
Adjacent
Gut health restoration, intestinal repair, and nutrient absorption optimization.
Systemic
GLP-3
Next-Gen GLP Research Compound
Adjacent
Advanced metabolic research and weight management via novel GLP pathways.
Systemic
Glow + KPV Blend
Anti-Inflammatory Glow
Adjacent
Skin health with anti-inflammatory and radiance support.
Systemic
Glow Blend
Skin Radiance Formula
Adjacent
Comprehensive skin radiance, anti-aging, and collagen support.
Systemic
Gonadorelin
GnRH
Adjacent
Stimulation of natural hormone production and fertility preservation during TRT.
Systemic
Kisspeptin
Metastin
Adjacent
Reproductive hormone regulation, fertility support, and libido enhancement.
Systemic
Melanotan I
Afamelanotide
Adjacent
UV-independent skin tanning and photoprotection.
Systemic
Melanotan II
MT-II
Adjacent
Skin tanning and libido enhancement.
Systemic
Melanotan II Nasal Spray
MT-II Nasal Spray
Adjacent
Convenient tanning and libido support via nasal delivery without injection.
Systemic
Oxytocin
The Bonding Hormone
Adjacent
Social bonding enhancement, trust facilitation, and stress reduction.
Systemic
Oxytocin Nasal Spray
Bonding Hormone Spray
Adjacent
Rapid social bonding and stress reduction via convenient nasal delivery.
Systemic
PT-141 (Bremelanotide)
Bremelanotide
Adjacent
Libido enhancement and sexual arousal in both men and women.
Systemic
PT-141 Nasal Spray
Bremelanotide Nasal Spray
Adjacent
Fast-acting sexual arousal support via convenient nasal delivery.
Systemic
SS Blend
Advanced Weight Management Blend
Adjacent
Advanced weight management via synergistic metabolic pathway targeting.
Systemic
Selank
Tuftsin Analog
Adjacent
Anxiety reduction, stress relief, and cognitive enhancement.
Systemic
Selank Nasal Spray
Selank Intranasal
Adjacent
Rapid anxiety relief and cognitive support via convenient nasal delivery.
Systemic
Semax
ACTH 4-7 Pro-Gly-Pro
Adjacent
Cognitive enhancement, focus, and neuroprotection.
Systemic
Semax + Selank Blend
Cognitive Calm Stack
Adjacent
Balanced cognitive enhancement combining stimulating focus with anxiolytic calm.
Systemic
Semax + Selank Nasal Spray
Dual Nootropic Nasal Spray
Adjacent
Dual nootropic and anxiolytic action via convenient combined nasal spray.
Systemic
Semax Nasal Spray
Semax Intranasal
Adjacent
Rapid cognitive enhancement and neuroprotection via convenient nasal delivery.
Systemic
Tesamorelin + Ipamorelin Blend
Premium GH Stack
Adjacent
Premium GH optimization with visceral fat reduction and body recomposition.
Systemic
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